Publications

Here are the publications of each member of our team.
Please feel free to contact us if you have any questions.

55: Moshkovits I, Kaminitz A, Reuveni D, Pasmanik-Chor M, Brazowski E, Mildner A, Leutz A, Zigmond E. Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis. Immun Inflamm Dis. 2022 Nov;10(11):e728. doi: 10.1002/iid3.728. PMID: 36301029; PMCID: PMC9609438.

54: Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Identification of environmental factors that promote intestinal inflammation. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. PMID: 36266581; PMCID: PMC9898826.

53: Dörr D, Obermayer B, Weiner JM, Zimmermann K, Anania C, Wagner LK, Lyras EM, Sapozhnikova V, Lara-Astiaso D, Prósper F, Lang R, Lupiáñez DG, Beule D, Höpken UE, Leutz A, Mildner A. C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages. Sci Immunol. 2022 Sep 16;7(75):eabj0140. doi: 10.1126/sciimmunol.abj0140. Epub 2022 Sep 16. PMID: 36112694.

52: Lyras EM, Zimmermann K, Wagner LK, Dörr D, Klose CSN, Fischer C, Jung S, Yona S, Hovav AH, Stenzel W, Dommerich S, Conrad T, Leutz A, Mildner A. Tongue immune compartment analysis reveals spatial macrophage heterogeneity. Elife. 2022 Jun 24;11:e77490. doi: 10.7554/eLife.77490. PMID: 35749158; PMCID: PMC9232218.

51: Steinkellner H, Kempaiah P, Beribisky AV, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam JP, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F. TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome. Int J Biol Macromol. 2022 Jun 1;209(Pt A):972-983. doi: 10.1016/j.ijbiomac.2022.04.080. Epub 2022 Apr 20. PMID: 35460749.

50: Rousselle A, Sonnemann J, Amann K, Mildner A, Lodka D, Kling L, Bieringer M, Schneider U, Leutz A, Enghard P, Kettritz R, Schreiber A. CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis. Ann Rheum Dis. 2022 Aug;81(8):1162-1172. doi: 10.1136/annrheumdis-2021-221984. Epub 2022 Apr 13. PMID: 35418479; PMCID: PMC9279749.

49: Ginhoux F, Mildner A, Gautier EL, Schlitzer A, Jakubzick C, Varol C, Bain C, Guermonprez P. Editorial: Monocyte Heterogeneity and Function. Front Immunol. 2021 Jan 7;11:626725. doi: 10.3389/fimmu.2020.626725. PMID: 33488633; PMCID: PMC7817760.

48: Wesolowski R, Kowenz-Leutz E, Zimmermann K, Dörr D, Hofstätter M, Slany RK, Mildner A, Leutz A. Myeloid transformation by MLL–ENL depends strictly on C/EBP. Life Sci Alliance. 2020 Nov 3;4(1):e202000709. doi: 10.26508/lsa.202000709. PMID: 33144337; PMCID: PMC7652399.

47: Giladi A, Wagner LK, Li H, Dörr D, Medaglia C, Paul F, Shemer A, Jung S, Yona S, Mack M, Leutz A, Amit I, Mildner A. Cxcl10⁺ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation. Nat Immunol. 2020 May;21(5):525-534. doi: 10.1038/s41590-020-0661-1. Epub 2020 Apr 20. Erratum in: Nat Immunol. 2020 Jun 8;: Erratum in: Nat Immunol. 2020 Jun 24;: PMID: 32313246.

46: de Laval B, Maurizio J, Kandalla PK, Brisou G, Simonnet L, Huber C, Gimenez G, Matcovitch-Natan O, Reinhardt S, David E, Mildner A, Leutz A, Nadel B, Bordi C, Amit I, Sarrazin S, Sieweke MH. C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells. Cell Stem Cell. 2020 May 7;26(5):657-674.e8. doi: 10.1016/j.stem.2020.01.017. Epub 2020 Mar 12. Erratum in: Cell Stem Cell. 2020 May 7;26(5):793. Erratum in: Cell Stem Cell. 2023 Jan 5;30(1):112. PMID: 32169166.

45: Mildner A, Yona S. Mapping the lung. Science. 2019 Mar 15;363(6432):1154-1155. doi: 10.1126/science.aaw6775. PMID: 30872510.

44: Yona S, Mildner A. Good things come in threes. Sci Immunol. 2018 Dec 7;3(30):eaav5545. doi: 10.1126/sciimmunol.aav5545. PMID: 30530728.

43: Guilliams M, Mildner A, Yona S. Developmental and Functional Heterogeneity of Monocytes. Immunity. 2018 Oct 16;49(4):595-613. doi: 10.1016/j.immuni.2018.10.005. PMID: 30332628.

42: Varol D, Mildner A, Blank T, Shemer A, Barashi N, Yona S, David E, Boura- Halfon S, Segal-Hayoun Y, Chappell-Maor L, Keren-Shaul H, Leshkowitz D, Hornstein E, Fuhrmann M, Amit I, Maggio N, Prinz M, Jung S. Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain. Immunity. 2017 Jun 20;46(6):1030-1044.e8. doi: 10.1016/j.immuni.2017.05.003. PMID: 28636953.

41: Mildner A. Ghosts in the shell: identification of microglia in the human central nervous system by P2Y12 receptor. Neural Regen Res. 2017 Apr;12(4):570-571. doi: 10.4103/1673-5374.205090. PMID: 28553330; PMCID: PMC5436348.

40: Mildner A, Schönheit J, Giladi A, David E, Lara-Astiaso D, Lorenzo-Vivas E, Paul F, Chappell-Maor L, Priller J, Leutz A, Amit I, Jung S. Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C Cells. Immunity. 2017 May 16;46(5):849-862.e7. doi: 10.1016/j.immuni.2017.04.018. PMID: 28514690.

39: Mildner A, Chapnik E, Varol D, Aychek T, Lampl N, Rivkin N, Bringmann A, Paul F, Boura-Halfon S, Hayoun YS, Barnett-Itzhaki Z, Amit I, Hornstein E, Jung S. MicroRNA-142 controls thymocyte proliferation. Eur J Immunol. 2017 Jul;47(7):1142-1152. doi: 10.1002/eji.201746987. Epub 2017 Jun 6. PMID: 28471480.

38: Wolf Y, Shemer A, Polonsky M, Gross M, Mildner A, Yona S, David E, Kim KW, Goldmann T, Amit I, Heikenwalder M, Nedospasov S, Prinz M, Friedman N, Jung S. Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation. J Exp Med. 2017 Apr 3;214(4):905-917. doi: 10.1084/jem.20160499. Epub 2017 Mar 22. PMID: 28330904; PMCID: PMC5379969.

37: Rivkin N, Chapnik E, Mildner A, Barshtein G, Porat Z, Kartvelishvily E, Dadosh T, Birger Y, Amir G, Yedgar S, Izraeli S, Jung S, Hornstein E. Erythrocyte survival is controlled by microRNA-142. Haematologica. 2017 Apr;102(4):676-685. doi: 10.3324/haematol.2016.156109. Epub 2016 Dec 1. PMID: 27909218; PMCID: PMC5395108.

36: Mildner A, Huang H, Radke J, Stenzel W, Priller J. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases. Glia. 2017 Feb;65(2):375-387. doi: 10.1002/glia.23097. Epub 2016 Nov 12. PMID: 27862351.

35: Mildner A, Marinkovic G, Jung S. Murine Monocytes: Origins, Subsets, Fates, and Functions. Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.MCHD-0033-2016. PMID: 27780020.

34: Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I. Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors. Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Erratum in: Cell. 2016 Jan 14;164(1-2):325. PMID: 26627738.

33: Varol C, Mildner A, Jung S. Macrophages: development and tissue specialization. Annu Rev Immunol. 2015;33:643-75. doi: 10.1146/annurev- immunol-032414-112220. PMID: 25861979.

32: Aychek T, Mildner A, Yona S, Kim KW, Lampl N, Reich-Zeliger S, Boon L, Yogev N, Waisman A, Cua DJ, Jung S. IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology. Nat Commun. 2015 Mar 12;6:6525. doi: 10.1038/ncomms7525. PMID: 25761673; PMCID: PMC4382688.

31: Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, Götz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, Lühder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, Müller M, Pukrop T, Mildner A, Kettenmann H, Brück W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. PMID: 25731696.

30: Lara-Astiaso D, Weiner A, Lorenzo-Vivas E, Zaretsky I, Jaitin DA, David E, Keren-Shaul H, Mildner A, Winter D, Jung S, Friedman N, Amit I. Immunogenetics. Chromatin state dynamics during blood formation. Science. 2014 Aug 22;345(6199):943-9. doi: 10.1126/science.1256271. Epub 2014 Aug 7. PMID: 25103404; PMCID: PMC4412442.

29: Chapnik E, Rivkin N, Mildner A, Beck G, Pasvolsky R, Metzl-Raz E, Birger Y, Amir G, Tirosh I, Porat Z, Israel LL, Lellouche E, Michaeli S, Lellouche JP, Izraeli S, Jung S, Hornstein E. miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis. Elife. 2014 May 23;3:e01964. doi: 10.7554/eLife.01964. PMID: 24859754; PMCID: PMC4067751.

28: Mildner A, Jung S. Development and function of dendritic cell subsets. Immunity. 2014 May 15;40(5):642-56. doi: 10.1016/j.immuni.2014.04.016. PMID: 24837101.

27: Jaitin DA, Kenigsberg E, Keren-Shaul H, Elefant N, Paul F, Zaretsky I, Mildner A, Cohen N, Jung S, Tanay A, Amit I. Massively parallel single-cell RNA- seq for marker-free decomposition of tissues into cell types. Science. 2014 Feb 14;343(6172):776-9. doi: 10.1126/science.1247651. PMID: 24531970; PMCID: PMC4412462.

26: Trobaugh DW, Gardner CL, Sun C, Haddow AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Nature. 2014 Feb 13;506(7487):245-8. doi: 10.1038/nature12869. Epub 2013 Dec 18. PMID: 24352241; PMCID: PMC4349380.

25: Dicken J, Mildner A, Leshkowitz D, Touw IP, Hantisteanu S, Jung S, Groner Y. Transcriptional reprogramming of CD11b+Esam(hi) dendritic cell identity and function by loss of Runx3. PLoS One. 2013 Oct 15;8(10):e77490. doi: 10.1371/journal.pone.0077490. PMID: 24204843; PMCID: PMC3817345.

24: Mildner A, Yona S, Jung S. A close encounter of the third kind: monocyte- derived cells. Adv Immunol. 2013;120:69-103. doi: 10.1016/B978-0-12-417028-5.00003-X. PMID: 24070381.

23: Ribes S, Regen T, Meister T, Tauber SC, Schütze S, Mildner A, Mack M, Hanisch UK, Nau R. Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect Immun. 2013 May;81(5):1810-9. doi: 10.1128/IAI.01349-12. Epub 2013 Mar 11. PMID: 23478323; PMCID: PMC3648016.

22: Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 2013 Jan 24;38(1):79-91. doi: 10.1016/j.immuni.2012.12.001. Epub 2012 Dec 27. Erratum in: Immunity. 2013 May 23;38(5):1073-9. PMID: 23273845; PMCID: PMC3908543.

21: Mildner A, Chapnik E, Manor O, Yona S, Kim KW, Aychek T, Varol D, Beck G, Itzhaki ZB, Feldmesser E, Amit I, Hornstein E, Jung S. Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Blood. 2013 Feb 7;121(6):1016-27. doi: 10.1182/blood-2012-07-445999. Epub 2012 Dec 4. PMID: 23212522.

20: Farago M, Rosenbluh C, Tevlin M, Fraenkel S, Schlesinger S, Masika H, Gouzman M, Teng G, Schatz D, Rais Y, Hanna JH, Mildner A, Jung S, Mostoslavsky G, Cedar H, Bergman Y. Clonal allelic predetermination of immunoglobulin-κ rearrangement. Nature. 2012 Oct 25;490(7421):561-5. doi: 10.1038/nature11496. Epub 2012 Sep 30. PMID: 23023124.

19: Ludin A, Itkin T, Gur-Cohen S, Mildner A, Shezen E, Golan K, Kollet O, Kalinkovich A, Porat Z, D’Uva G, Schajnovitz A, Voronov E, Brenner DA, Apte RN, Jung S, Lapidot T. Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat Immunol. 2012 Nov;13(11):1072-82. doi: 10.1038/ni.2408. Epub 2012 Sep 16. PMID: 22983360.

18: Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S, Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E, MacPherson A, Manz MG, Weber A, Browning JL, Arkan MC, Rülicke T, Aguzzi A, Prinz M, Graf R, Heikenwalder M. Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology. 2012 Nov;143(5):1361-1374. doi: 10.1053/j.gastro.2012.07.112. Epub 2012 Aug 2. PMID: 22863765.

17: Poppensieker K, Otte DM, Schürmann B, Limmer A, Dresing P, Drews E, Schumak B, Klotz L, Raasch J, Mildner A, Waisman A, Scheu S, Knolle P, Förster I, Prinz M, Maier W, Zimmer A, Alferink J. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3897-902. doi: 10.1073/pnas.1114153109. Epub 2012 Feb 21. PMID: 22355103; PMCID: PMC3309768.

16: Mildner A, Schlevogt B, Kierdorf K, Böttcher C, Erny D, Kummer MP, Quinn M, Brück W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer’s disease. J Neurosci. 2011 Aug 3;31(31):11159-71. doi: 10.1523/JNEUROSCI.6209-10.2011. PMID: 21813677; PMCID: PMC6623351.

15: Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Del Turco D, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M. IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain. 2011 Apr;134(Pt 4):1184-98. doi: 10.1093/brain/awq359. Epub 2011 Feb 10. PMID: 21310728; PMCID: PMC4055835.

14: Prinz M, Mildner A. Microglia in the CNS: immigrants from another world. Glia. 2011 Feb;59(2):177-87. doi: 10.1002/glia.21104. PMID: 21125659.

13: Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, Steinman L, Becker C, Bogdahn U, Neurath MF, Steinbrecher A, Waisman A. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain. 2010 Apr;133(Pt 4):1067-81. doi: 10.1093/brain/awq039. Epub 2010 Mar 30. PMID: 20354004; PMCID: PMC2850583.

12: Mildner A, Mack M, Schmidt H, Brück W, Djukic M, Zabel MD, Hille A, Priller J, Prinz M. CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain. 2009 Sep;132(Pt 9):2487-500. doi: 10.1093/brain/awp144. Epub 2009 Jun 16. PMID: 19531531.

11: Eixarch H, Espejo C, Gómez A, Mansilla MJ, Castillo M, Mildner A, Vidal F, Gimeno R, Prinz M, Montalban X, Barquinero J. Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen. Mol Ther. 2009 May;17(5):897-905. doi: 10.1038/mt.2009.42. Epub 2009 Mar 10. Erratum in: Mol Ther. 2009 Jul;17(7):1303. Erratum in: Mol Ther. 2009 Jul;17(7):1303. PMID: 19277013; PMCID: PMC2835141.

10: Ribes S, Ebert S, Czesnik D, Regen T, Zeug A, Bukowski S, Mildner A, Eiffert H, Hanisch UK, Hammerschmidt S, Nau R. Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect Immun. 2009 Jan;77(1):557-64. doi: 10.1128/IAI.00903-08. Epub 2008 Nov 3. PMID: 18981243; PMCID: PMC2612236.

9: Mildner A, Djukic M, Garbe D, Wellmer A, Kuziel WA, Mack M, Nau R, Prinz M. Ly-6G+CCR2- myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system. J Immunol. 2008 Aug 15;181(4):2713-22. doi: 10.4049/jimmunol.181.4.2713. PMID: 18684962.

8: Prinz M, Schmidt H, Mildner A, Knobeloch KP, Hanisch UK, Raasch J, Merkler D, Detje C, Gutcher I, Mages J, Lang R, Martin R, Gold R, Becher B, Brück W, Kalinke U. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity. 2008 May;28(5):675-86. doi: 10.1016/j.immuni.2008.03.011. PMID: 18424188.

7: Mildner A, Schmidt H, Nitsche M, Merkler D, Hanisch UK, Mack M, Heikenwalder M, Brück W, Priller J, Prinz M. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci. 2007 Dec;10(12):1544-53. doi: 10.1038/nn2015. Epub 2007 Nov 18. PMID: 18026096.

6: Kassmann CM, Lappe-Siefke C, Baes M, Brügger B, Mildner A, Werner HB, Natt O, Michaelis T, Prinz M, Frahm J, Nave KA. Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet. 2007 Aug;39(8):969-76. doi: 10.1038/ng2070. Epub 2007 Jul 22. PMID: 17643102.

5: van Loo G, De Lorenzi R, Schmidt H, Huth M, Mildner A, Schmidt-Supprian M, Lassmann H, Prinz MR, Pasparakis M. Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice. Nat Immunol. 2006 Sep;7(9):954-61. doi: 10.1038/ni1372. Epub 2006 Aug 6. PMID: 16892069.

4: Djukic M, Mildner A, Schmidt H, Czesnik D, Brück W, Priller J, Nau R, Prinz M. Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain. 2006 Sep;129(Pt 9):2394-403. doi: 10.1093/brain/awl206. Epub 2006 Aug 3. PMID: 16891321.

3: Herrmann I, Kellert M, Schmidt H, Mildner A, Hanisch UK, Brück W, Prinz M, Nau R. Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect Immun. 2006 Aug;74(8):4841-8. doi: 10.1128/IAI.00026-06. PMID: 16861672; PMCID: PMC1539614.

2: Prinz M, Garbe F, Schmidt H, Mildner A, Gutcher I, Wolter K, Piesche M, Schroers R, Weiss E, Kirschning CJ, Rochford CD, Brück W, Becher B. Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest. 2006 Feb;116(2):456-64. doi: 10.1172/JCI26078. Epub 2006 Jan 26. PMID: 16440059; PMCID: PMC1350999.

1: Grönke S, Mildner A, Fellert S, Tennagels N, Petry S, Müller G, Jäckle H, Kühnlein RP. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab. 2005 May;1(5):323-30. doi: 10.1016/j.cmet.2005.04.003. PMID: 16054079.

24. Makkonen K, Jännäri M, Crisóstomo L, Kuusi M, Patyra K, … Kero J. Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T knock-in model. JCI Insight. 2024 Jan 9:e167092. doi: 10.1172/jci.insight.167092. Epub ahead of print. PMID: 38194289.

23. Pinto, Soraia, Bárbara Guerra-Carvalho, Luís Crisóstomo, António Rocha, Alberto Barros, Marco G. Alves, and Pedro F. Oliveira. 2024. “Metabolomics Integration in Assisted Reproductive Technologies for Enhanced Embryo Selection beyond Morphokinetic Analysis” International Journal of Molecular Sciences 25, no. 1: 491. https://doi.org/10.3390/ijms25010491

22. Crisóstomo, L., Oliveira, P.F. & Alves, M.G. A systematic scientometric review of paternal inheritance of acquired metabolic traits. BMC Biol21, 255 (2023). https://doi.org/10.1186/s12915-023-01744-6

21. Chaiyasoot, K., Sakai, N. S., Zakeri, R., Makaronidis, J., Crisóstomo, L., Alves, M. G., … & Batterham, R. L. (2023). Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery. Obesity Surgery, 1-11. https://doi.org/10.1007/s11695-023-06905-8

20. Agarwal A, Cannarella R, Saleh R, Boitrelle F, Gül M, Toprak T, Salvio G, Arafa M, Russo GI, Harraz AM, Singh R, Garrido N, Hamoda TAAAM, Rambhatla A, Kavoussi P, Kuroda S, Çalik G, Saini P, Ceyhan E, Dimitriadis F, Henkel R, Crafa A, Palani A, Duran MB, Maziotis E, Saïs É, Bendayan M, Darbandi M, Le TV, Gunes S, Tsioulou P, Sengupta P, Hazir B, Çeker G, Darbandi S, Durairajanayagam D, Aghamajidi A, Alkhalidi N, Sogutdelen E, Leisegang K, Alarbid A, Ho CCK, Malhotra V, Finocchi F, Crisóstomo L, Kosgi R, ElBardisi H, Zini A, Birowo P, Colpi G, Park HJ, Serefoglu EC, Nguyen Q, Ko E, de la Rosette J, Pinggera GM, Nguyen HVP, Kandil H, Shah R (2022). Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis. World Journal of Men’s Health, 40. doi:10.5534/wjmh.220142

19. Crisóstomo L, Oliveira PF, Alves MG (2022). Antioxidants, Oxidative Stress, and Non-Communicable Diseases. Antioxidants, 11(6):1080. doi:10.3390/antiox11061080

18. Crisóstomo L, Bourgery M, Rato L, Raposo JF, Batterham RL, Kotaja N, Alves MG (2022). Testicular “inherited metabolic memory” of ancestral high-fat diet is associated with sperm sncRNA content. Biomedicines (Basel), 10(4):909. doi: 10.3390/biomedicines10040909

17. Agarwal A, Finelli R, Durairajanayagam D, Leisegang K, Henkel R, Salvio G, Aghamajidi A, Sengupta P, Crisóstomo L, Tsioulou PA, Roychoudhury S, Finocchi F, Darbandi M, Mottola F, Darbandi S, Iovine C, Santonastaso M, Zaker H, Kesari KK, Nomanzadeh A, Gugnani N, Rambhatla A, Duran MB, Ceyhan E, Kandil H, Arafa M, Saleh R, Shah Rupin, Boitrelle F (2022) Comprehensive Analysis of Global Research on Human Varicocele: A Scientometric Approach. World Journal of Men’s Health, 40. doi:10.5534/wjmh.210202

16. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T, Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2022) Inherited Metabolic Memory of High-fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters. Molecular Nutrition & Food Research, 2100680. doi:10.1002/mnfr.202100680

15. Guerra-Carvalho B*, Carrageta DF*, Crisóstomo L*, Carvalho RA, Alves MG, Oliveira PF (2021). Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects. Animal reproduction science, 106896. doi:10.1016/j.anireprosci.2021.106896

14. Crisóstomo L, Jarak I, Rato L, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2021). Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice. Scientific Reports, 11(1), 9444. doi:10.1038/s41598-021-88981-3

13. Crisóstomo L, Oliveira PF, Alves MG (2021) Sperm, metabolic memory, and echoes from Lamarck. European Journal of Clinical Investigation. doi:10.1111/eci.13492

12. Pereira SC*, Crisóstomo L*, Sousa M, Oliveira PF, Alves MG (2020) Metabolic diseases affect male reproduction and induce signatures in gametes that may compromise the offspring health. Environmental Epigenetics, 6. doi:10.1093/eep/dvaa019

11. Crisóstomo L, Videira RA, Jarak I, Starčević K, Mašek T, Rato LP, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2020) Diet during early life defines testicular lipid content and sperm quality in adulthood. American Journal of Physiology-Endocrinology & Metabolism 319: E1061–E1073. doi:10.1152/ajpendo.00235.2020

10. Crisóstomo L, Pereira SC, Monteiro MP, Raposo JF, Oliveira PF, Alves MG (2020) Lifestyle, metabolic disorders and male hypogonadism – A one-way ticket? Molecular and Cellular Endocrinology, 110945. doi: 10.1016/j.mce.2020.110945

9. Crisóstomo L, Rato L, Jarak I, Silva BM, Raposo JF, Batterham RL, Oliveira PF, Alves MG (2019) A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome. Reproduction 158(4), 377–387. doi: 10.1530/REP-19-0259

8. Boussada M, Dias TR, Crisóstomo L, Akacha AB, Ali RB, El May MV, Alves MG, Oliveira PF (2019) A new thiocyanoacetamide (2-cyano-2-p-nitrophenyl-N-benzylthioamide) reduces doxorubicin-induced in vitro toxicity in Sertoli cells by decreasing apoptosis and autophagy. Theriogenology 140, 188-200. doi: 10.1016/j.theriogenology.2019.08.030

7. Crisóstomo L, Alves MG, Gorga A, Sousa M, Riera MF, Galardo MN, Meroni SB, Oliveira PF (2018) Molecular mechanisms and signalling pathways involved in the nutritional support of spermatogenesis by Sertoli cells. In: Alves MG, Oliveira PF (eds) Sertoli cells – Methods and Protocols. Methods in Molecular Biology, vol 1748, 1 edn. Humana Press, pp 129-155. doi:10.1007/978-1-4939-7698-0

6. Oliveira PF, Crisóstomo L, Sousa M, Monteiro MP, Macedo P, Raposo J, Alves MG (2017). O papel do Espermatozoide na Transmissão à Descendência do Risco para Diabetes Mellitus. [The Role of Sperm in the Transmission to the Offspring of the Risk for Diabetes Mellitus]. Revista Portuguesa de Diabetes. 12(4): 149-158.

5. Crisóstomo L, Alves MG, Calamita G, Sousa M, Oliveira PF (2017) Glycerol and testicular activity: the good, the bad and the ugly. Molecular Human Reproduction. 23(9), 583-655. doi: 10.1093/molehr/gax049

4. Costa AM, Grazina C, Miragaia D, Crisóstomo L, Carvalho PG (2017) Sports development environment in swimming clubs: a preliminary study on Portuguese swimmers’ perceptions. Revista Iberoamericana de Psicología del Ejercicio y el Deport. 12(2), 231-236.

3. Crisóstomo L, Sousa M, Alves MG, Oliveira PF (2017) The Burden of Metabolic Diseases on Male Reproductive Health. International Journal of Diabetology & Vascular Disease Research. 5(1e), 1-2. doi: dx.doi.org/10.19070/2328-353X-1700012e

2. Casanova N, Palmeira-de-Oliveira A, Pereira A, Crisóstomo L, Travassos B, Costa AM (2016) Cortisol, testosterone and mood state variation during an official female football competition. The Journal of Sports Medicine and Physical Fitness, 56(6), 775-781.

1. Costa AM, Dias A, Crisóstomo L, Ramalhinho A, Breitenfeld L, Pereira A (2014) GlutathioneS-Transferase M1 and T1 genotypes in high-level swimmers: original research. International SportMed Journal, 15(4), 458-465.

2. Examining the roles of M-CSF, GM-CSF, and G-CSF in thymic macrophage maintenance by using Fc-fusion proteins and antibody blocking (2022) Parena Aeron Jade, Dzhagalov Ivan (Pro gradu, diplomityö, ylempi amk-opinnäytetyö (G2))

1. Lytic phages display protective effects against soft rot-causing Pectobacterium sp. (2022) Parena Aeron Jade, Silva Benji Brayan, Mercado Rae Mark, Sendon Adelbert Adrian, Signabon Freddieweb, Balidion Johnny, and Encabo Jaymee(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

3.Hyseni Besmir, Mazreku Ilir and Bislimi Kemajl*, The Role of Graphene Oxide in the Inhibition of Migration and Invasion of Cancer Cells by Destroying Actin Cytoskeleton and via Inhibiting the Activities of ETC Complexes, Current Cancer Therapy Reviews 2023; 19(2)

2. “The role of immune cells in the transport of the Chlamydia muridarum from the iliac lymph nodes to the spleen and the gastrointestinal tract in mice”. (On embargo until mid-2023) https://books.google.fi/books/about/The_Role_of_Immune_Cells_in_Transport_of.html?id=WTmrzgEACAAJ&redir_esc=y)

1. Shillova, N., Howe, S. E., Hyseni, B., Ridgell, D., Fisher, D. J., & Konjufca, V. (2020). Chlamydia-specific IgA secretion in the female reproductive tract induced via per-oral immunization confers protection against primary Chlamydia challenge. Infection and Immunity, 89(1), e00413-20.

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