1: Moshkovits I, Kaminitz A, Reuveni D, Pasmanik-Chor M, Brazowski E, Mildner A, Leutz A, Zigmond E. Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis. Immun Inflamm Dis. 2022 Nov;10(11):e728. doi: 10.1002/iid3.728. PMID: 36301029; PMCID: PMC9609438.

2: Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Identification of environmental factors that promote intestinal inflammation. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. PMID: 36266581; PMCID: PMC9898826.

3: Dörr D, Obermayer B, Weiner JM, Zimmermann K, Anania C, Wagner LK, Lyras EM, Sapozhnikova V, Lara-Astiaso D, Prósper F, Lang R, Lupiáñez DG, Beule D, Höpken UE, Leutz A, Mildner A. C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages. Sci Immunol. 2022 Sep 16;7(75):eabj0140. doi: 10.1126/sciimmunol.abj0140. Epub 2022 Sep 16. PMID: 36112694.

4: Lyras EM, Zimmermann K, Wagner LK, Dörr D, Klose CSN, Fischer C, Jung S, Yona S, Hovav AH, Stenzel W, Dommerich S, Conrad T, Leutz A, Mildner A. Tongue immune compartment analysis reveals spatial macrophage heterogeneity. Elife. 2022 Jun 24;11:e77490. doi: 10.7554/eLife.77490. PMID: 35749158; PMCID: PMC9232218.

5: Steinkellner H, Kempaiah P, Beribisky AV, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam JP, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F. TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome. Int J Biol Macromol. 2022 Jun 1;209(Pt A):972-983. doi: 10.1016/j.ijbiomac.2022.04.080. Epub 2022 Apr 20. PMID: 35460749.

6: Rousselle A, Sonnemann J, Amann K, Mildner A, Lodka D, Kling L, Bieringer M, Schneider U, Leutz A, Enghard P, Kettritz R, Schreiber A. CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis. Ann Rheum Dis. 2022 Aug;81(8):1162-1172. doi: 10.1136/annrheumdis-2021-221984. Epub 2022 Apr 13. PMID: 35418479; PMCID: PMC9279749.

7: Ginhoux F, Mildner A, Gautier EL, Schlitzer A, Jakubzick C, Varol C, Bain C, Guermonprez P. Editorial: Monocyte Heterogeneity and Function. Front Immunol. 2021 Jan 7;11:626725. doi: 10.3389/fimmu.2020.626725. PMID: 33488633; PMCID: PMC7817760.

8: Wesolowski R, Kowenz-Leutz E, Zimmermann K, Dörr D, Hofstätter M, Slany RK, Mildner A, Leutz A. Myeloid transformation by MLL–ENL depends strictly on C/EBP. Life Sci Alliance. 2020 Nov 3;4(1):e202000709. doi: 10.26508/lsa.202000709. PMID: 33144337; PMCID: PMC7652399.

9: Giladi A, Wagner LK, Li H, Dörr D, Medaglia C, Paul F, Shemer A, Jung S, Yona S, Mack M, Leutz A, Amit I, Mildner A. Cxcl10⁺ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation. Nat Immunol. 2020 May;21(5):525-534. doi: 10.1038/s41590-020-0661-1. Epub 2020 Apr 20. Erratum in: Nat Immunol. 2020 Jun 8;: Erratum in: Nat Immunol. 2020 Jun 24;: PMID: 32313246.

10: de Laval B, Maurizio J, Kandalla PK, Brisou G, Simonnet L, Huber C, Gimenez G, Matcovitch-Natan O, Reinhardt S, David E, Mildner A, Leutz A, Nadel B, Bordi C, Amit I, Sarrazin S, Sieweke MH. C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells. Cell Stem Cell. 2020 May 7;26(5):657-674.e8. doi: 10.1016/j.stem.2020.01.017. Epub 2020 Mar 12. Erratum in: Cell Stem Cell. 2020 May 7;26(5):793. Erratum in: Cell Stem Cell. 2023 Jan 5;30(1):112. PMID: 32169166.

11: Mildner A, Yona S. Mapping the lung. Science. 2019 Mar 15;363(6432):1154-1155. doi: 10.1126/science.aaw6775. PMID: 30872510.

12: Yona S, Mildner A. Good things come in threes. Sci Immunol. 2018 Dec 7;3(30):eaav5545. doi: 10.1126/sciimmunol.aav5545. PMID: 30530728.

13: Guilliams M, Mildner A, Yona S. Developmental and Functional Heterogeneity of Monocytes. Immunity. 2018 Oct 16;49(4):595-613. doi: 10.1016/j.immuni.2018.10.005. PMID: 30332628.

14: Varol D, Mildner A, Blank T, Shemer A, Barashi N, Yona S, David E, Boura- Halfon S, Segal-Hayoun Y, Chappell-Maor L, Keren-Shaul H, Leshkowitz D, Hornstein E, Fuhrmann M, Amit I, Maggio N, Prinz M, Jung S. Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain. Immunity. 2017 Jun 20;46(6):1030-1044.e8. doi: 10.1016/j.immuni.2017.05.003. PMID: 28636953.

15: Mildner A. Ghosts in the shell: identification of microglia in the human central nervous system by P2Y12 receptor. Neural Regen Res. 2017 Apr;12(4):570-571. doi: 10.4103/1673-5374.205090. PMID: 28553330; PMCID: PMC5436348.

16: Mildner A, Schönheit J, Giladi A, David E, Lara-Astiaso D, Lorenzo-Vivas E, Paul F, Chappell-Maor L, Priller J, Leutz A, Amit I, Jung S. Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C Cells. Immunity. 2017 May 16;46(5):849-862.e7. doi: 10.1016/j.immuni.2017.04.018. PMID: 28514690.

17: Mildner A, Chapnik E, Varol D, Aychek T, Lampl N, Rivkin N, Bringmann A, Paul F, Boura-Halfon S, Hayoun YS, Barnett-Itzhaki Z, Amit I, Hornstein E, Jung S. MicroRNA-142 controls thymocyte proliferation. Eur J Immunol. 2017 Jul;47(7):1142-1152. doi: 10.1002/eji.201746987. Epub 2017 Jun 6. PMID: 28471480.

18: Wolf Y, Shemer A, Polonsky M, Gross M, Mildner A, Yona S, David E, Kim KW, Goldmann T, Amit I, Heikenwalder M, Nedospasov S, Prinz M, Friedman N, Jung S. Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation. J Exp Med. 2017 Apr 3;214(4):905-917. doi: 10.1084/jem.20160499. Epub 2017 Mar 22. PMID: 28330904; PMCID: PMC5379969.

19: Rivkin N, Chapnik E, Mildner A, Barshtein G, Porat Z, Kartvelishvily E, Dadosh T, Birger Y, Amir G, Yedgar S, Izraeli S, Jung S, Hornstein E. Erythrocyte survival is controlled by microRNA-142. Haematologica. 2017 Apr;102(4):676-685. doi: 10.3324/haematol.2016.156109. Epub 2016 Dec 1. PMID: 27909218; PMCID: PMC5395108.

20: Mildner A, Huang H, Radke J, Stenzel W, Priller J. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases. Glia. 2017 Feb;65(2):375-387. doi: 10.1002/glia.23097. Epub 2016 Nov 12. PMID: 27862351.

21: Mildner A, Marinkovic G, Jung S. Murine Monocytes: Origins, Subsets, Fates, and Functions. Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.MCHD-0033-2016. PMID: 27780020.

22: Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I. Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors. Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Erratum in: Cell. 2016 Jan 14;164(1-2):325. PMID: 26627738.

23: Varol C, Mildner A, Jung S. Macrophages: development and tissue specialization. Annu Rev Immunol. 2015;33:643-75. doi: 10.1146/annurev- immunol-032414-112220. PMID: 25861979.

24: Aychek T, Mildner A, Yona S, Kim KW, Lampl N, Reich-Zeliger S, Boon L, Yogev N, Waisman A, Cua DJ, Jung S. IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology. Nat Commun. 2015 Mar 12;6:6525. doi: 10.1038/ncomms7525. PMID: 25761673; PMCID: PMC4382688.

25: Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, Götz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, Lühder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, Müller M, Pukrop T, Mildner A, Kettenmann H, Brück W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. PMID: 25731696.

26: Lara-Astiaso D, Weiner A, Lorenzo-Vivas E, Zaretsky I, Jaitin DA, David E, Keren-Shaul H, Mildner A, Winter D, Jung S, Friedman N, Amit I. Immunogenetics. Chromatin state dynamics during blood formation. Science. 2014 Aug 22;345(6199):943-9. doi: 10.1126/science.1256271. Epub 2014 Aug 7. PMID: 25103404; PMCID: PMC4412442.

27: Chapnik E, Rivkin N, Mildner A, Beck G, Pasvolsky R, Metzl-Raz E, Birger Y, Amir G, Tirosh I, Porat Z, Israel LL, Lellouche E, Michaeli S, Lellouche JP, Izraeli S, Jung S, Hornstein E. miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis. Elife. 2014 May 23;3:e01964. doi: 10.7554/eLife.01964. PMID: 24859754; PMCID: PMC4067751.

28: Mildner A, Jung S. Development and function of dendritic cell subsets. Immunity. 2014 May 15;40(5):642-56. doi: 10.1016/j.immuni.2014.04.016. PMID: 24837101.

29: Jaitin DA, Kenigsberg E, Keren-Shaul H, Elefant N, Paul F, Zaretsky I, Mildner A, Cohen N, Jung S, Tanay A, Amit I. Massively parallel single-cell RNA- seq for marker-free decomposition of tissues into cell types. Science. 2014 Feb 14;343(6172):776-9. doi: 10.1126/science.1247651. PMID: 24531970; PMCID: PMC4412462.

30: Trobaugh DW, Gardner CL, Sun C, Haddow AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Nature. 2014 Feb 13;506(7487):245-8. doi: 10.1038/nature12869. Epub 2013 Dec 18. PMID: 24352241; PMCID: PMC4349380.

31: Dicken J, Mildner A, Leshkowitz D, Touw IP, Hantisteanu S, Jung S, Groner Y. Transcriptional reprogramming of CD11b+Esam(hi) dendritic cell identity and function by loss of Runx3. PLoS One. 2013 Oct 15;8(10):e77490. doi: 10.1371/journal.pone.0077490. PMID: 24204843; PMCID: PMC3817345.

32: Mildner A, Yona S, Jung S. A close encounter of the third kind: monocyte- derived cells. Adv Immunol. 2013;120:69-103. doi: 10.1016/B978-0-12-417028-5.00003-X. PMID: 24070381.

33: Ribes S, Regen T, Meister T, Tauber SC, Schütze S, Mildner A, Mack M, Hanisch UK, Nau R. Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect Immun. 2013 May;81(5):1810-9. doi: 10.1128/IAI.01349-12. Epub 2013 Mar 11. PMID: 23478323; PMCID: PMC3648016.

34: Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 2013 Jan 24;38(1):79-91. doi: 10.1016/j.immuni.2012.12.001. Epub 2012 Dec 27. Erratum in: Immunity. 2013 May 23;38(5):1073-9. PMID: 23273845; PMCID: PMC3908543.

35: Mildner A, Chapnik E, Manor O, Yona S, Kim KW, Aychek T, Varol D, Beck G, Itzhaki ZB, Feldmesser E, Amit I, Hornstein E, Jung S. Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Blood. 2013 Feb 7;121(6):1016-27. doi: 10.1182/blood-2012-07-445999. Epub 2012 Dec 4. PMID: 23212522.

36: Farago M, Rosenbluh C, Tevlin M, Fraenkel S, Schlesinger S, Masika H, Gouzman M, Teng G, Schatz D, Rais Y, Hanna JH, Mildner A, Jung S, Mostoslavsky G, Cedar H, Bergman Y. Clonal allelic predetermination of immunoglobulin-κ rearrangement. Nature. 2012 Oct 25;490(7421):561-5. doi: 10.1038/nature11496. Epub 2012 Sep 30. PMID: 23023124.

37: Ludin A, Itkin T, Gur-Cohen S, Mildner A, Shezen E, Golan K, Kollet O, Kalinkovich A, Porat Z, D’Uva G, Schajnovitz A, Voronov E, Brenner DA, Apte RN, Jung S, Lapidot T. Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat Immunol. 2012 Nov;13(11):1072-82. doi: 10.1038/ni.2408. Epub 2012 Sep 16. PMID: 22983360.

38: Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S, Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E, MacPherson A, Manz MG, Weber A, Browning JL, Arkan MC, Rülicke T, Aguzzi A, Prinz M, Graf R, Heikenwalder M. Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology. 2012 Nov;143(5):1361-1374. doi: 10.1053/j.gastro.2012.07.112. Epub 2012 Aug 2. PMID: 22863765.

39: Poppensieker K, Otte DM, Schürmann B, Limmer A, Dresing P, Drews E, Schumak B, Klotz L, Raasch J, Mildner A, Waisman A, Scheu S, Knolle P, Förster I, Prinz M, Maier W, Zimmer A, Alferink J. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3897-902. doi: 10.1073/pnas.1114153109. Epub 2012 Feb 21. PMID: 22355103; PMCID: PMC3309768.

40: Mildner A, Schlevogt B, Kierdorf K, Böttcher C, Erny D, Kummer MP, Quinn M, Brück W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer’s disease. J Neurosci. 2011 Aug 3;31(31):11159-71. doi: 10.1523/JNEUROSCI.6209-10.2011. PMID: 21813677; PMCID: PMC6623351.

41: Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Del Turco D, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M. IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain. 2011 Apr;134(Pt 4):1184-98. doi: 10.1093/brain/awq359. Epub 2011 Feb 10. PMID: 21310728; PMCID: PMC4055835.

42: Prinz M, Mildner A. Microglia in the CNS: immigrants from another world. Glia. 2011 Feb;59(2):177-87. doi: 10.1002/glia.21104. PMID: 21125659.

43: Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, Steinman L, Becker C, Bogdahn U, Neurath MF, Steinbrecher A, Waisman A. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain. 2010 Apr;133(Pt 4):1067-81. doi: 10.1093/brain/awq039. Epub 2010 Mar 30. PMID: 20354004; PMCID: PMC2850583.

44: Mildner A, Mack M, Schmidt H, Brück W, Djukic M, Zabel MD, Hille A, Priller J, Prinz M. CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain. 2009 Sep;132(Pt 9):2487-500. doi: 10.1093/brain/awp144. Epub 2009 Jun 16. PMID: 19531531.

45: Eixarch H, Espejo C, Gómez A, Mansilla MJ, Castillo M, Mildner A, Vidal F, Gimeno R, Prinz M, Montalban X, Barquinero J. Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen. Mol Ther. 2009 May;17(5):897-905. doi: 10.1038/mt.2009.42. Epub 2009 Mar 10. Erratum in: Mol Ther. 2009 Jul;17(7):1303. Erratum in: Mol Ther. 2009 Jul;17(7):1303. PMID: 19277013; PMCID: PMC2835141.

46: Ribes S, Ebert S, Czesnik D, Regen T, Zeug A, Bukowski S, Mildner A, Eiffert H, Hanisch UK, Hammerschmidt S, Nau R. Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect Immun. 2009 Jan;77(1):557-64. doi: 10.1128/IAI.00903-08. Epub 2008 Nov 3. PMID: 18981243; PMCID: PMC2612236.

47: Mildner A, Djukic M, Garbe D, Wellmer A, Kuziel WA, Mack M, Nau R, Prinz M. Ly-6G+CCR2- myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system. J Immunol. 2008 Aug 15;181(4):2713-22. doi: 10.4049/jimmunol.181.4.2713. PMID: 18684962.

48: Prinz M, Schmidt H, Mildner A, Knobeloch KP, Hanisch UK, Raasch J, Merkler D, Detje C, Gutcher I, Mages J, Lang R, Martin R, Gold R, Becher B, Brück W, Kalinke U. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity. 2008 May;28(5):675-86. doi: 10.1016/j.immuni.2008.03.011. PMID: 18424188.

49: Mildner A, Schmidt H, Nitsche M, Merkler D, Hanisch UK, Mack M, Heikenwalder M, Brück W, Priller J, Prinz M. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci. 2007 Dec;10(12):1544-53. doi: 10.1038/nn2015. Epub 2007 Nov 18. PMID: 18026096.

50: Kassmann CM, Lappe-Siefke C, Baes M, Brügger B, Mildner A, Werner HB, Natt O, Michaelis T, Prinz M, Frahm J, Nave KA. Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet. 2007 Aug;39(8):969-76. doi: 10.1038/ng2070. Epub 2007 Jul 22. PMID: 17643102.

51: van Loo G, De Lorenzi R, Schmidt H, Huth M, Mildner A, Schmidt-Supprian M, Lassmann H, Prinz MR, Pasparakis M. Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice. Nat Immunol. 2006 Sep;7(9):954-61. doi: 10.1038/ni1372. Epub 2006 Aug 6. PMID: 16892069.

52: Djukic M, Mildner A, Schmidt H, Czesnik D, Brück W, Priller J, Nau R, Prinz M. Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain. 2006 Sep;129(Pt 9):2394-403. doi: 10.1093/brain/awl206. Epub 2006 Aug 3. PMID: 16891321.

53: Herrmann I, Kellert M, Schmidt H, Mildner A, Hanisch UK, Brück W, Prinz M, Nau R. Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect Immun. 2006 Aug;74(8):4841-8. doi: 10.1128/IAI.00026-06. PMID: 16861672; PMCID: PMC1539614.

54: Prinz M, Garbe F, Schmidt H, Mildner A, Gutcher I, Wolter K, Piesche M, Schroers R, Weiss E, Kirschning CJ, Rochford CD, Brück W, Becher B. Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest. 2006 Feb;116(2):456-64. doi: 10.1172/JCI26078. Epub 2006 Jan 26. PMID: 16440059; PMCID: PMC1350999.

55: Grönke S, Mildner A, Fellert S, Tennagels N, Petry S, Müller G, Jäckle H, Kühnlein RP. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab. 2005 May;1(5):323-30. doi: 10.1016/j.cmet.2005.04.003. PMID: 16054079.